Specification
| Description | Recombinant protein from the full-length sequence of homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 2 (NM_001040151). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9NY72 |
| Entry Name | SCN3B_HUMAN |
| Gene Names | SCN3B KIAA1158 |
| Alternative Gene Names | KIAA1158 |
| Alternative Protein Names | Sodium channel subunit beta-3 |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 215 |
| Molecular Weight(Da) | 24702 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE |
Background
| Function | FUNCTION: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity). {ECO:0000250}. |
| Pathway | |
| Protein Families | Sodium channel auxiliary subunit SCN3B (TC 8.A.17) family |
| Tissue Specificity | Expressed in the atrium. {ECO:0000269|PubMed:21051419}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |